Small cell lung cancer: Time to revisit DNA-damaging chemotherapy-Reference-Cited by-同舟云学术

Small cell lung cancer: Time to revisit DNA-damaging chemotherapy

Published:2016-07-06 Issue:346 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Thomas Anish¹,Pommier Yves²

Affiliation:

1. Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

2. Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

Abstract

Rational use of DNA-damaging chemotherapy, with new combinations to heighten DNA replication stress, could improve outcomes in small cell lung cancer.

Funder

NCI

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference10 articles.

1. Hallmarks of Cancer: The Next Generation

2. Comprehensive genomic profiles of small cell lung cancer

3. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

4. CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist

5. Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

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