Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models-Reference-Cited by-同舟云学术

Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models

Published:2021-08-11 Issue:606 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Martinez-Usatorre Amaia¹²^ORCID,Kadioglu Ece¹^ORCID,Boivin Gael¹²^ORCID,Cianciaruso Chiara¹²^ORCID,Guichard Alan¹²^ORCID,Torchia Bruno¹²^ORCID,Zangger Nadine³^ORCID,Nassiri Sina¹²³,Keklikoglou Ioanna¹^ORCID,Schmittnaegel Martina¹⁴,Ries Carola H.⁴^ORCID,Meylan Etienne¹^ORCID,De Palma Michele¹²^ORCID

Affiliation:

1. Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland.

2. Agora Cancer Research Center, 1011 Lausanne, Switzerland.

3. Bioinformatics Core Facility (BCF), SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.

4. Roche Innovation Center Munich, Oncology Discovery, Pharma Research and Early Development, 82377 Penzberg, Germany.

Abstract

Lung cancer resistance to PD-1 inhibition can be overcome by targeting tumor-associated macrophages in mouse models.

Funder

H2020 European Research Council

Swiss Cancer League

FUNDING

Publisher

American Association for the Advancement of Science (AAAS)

Subject