Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans-Reference-Cited by-同舟云学术

Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans

Published:2020-12-09 Issue:573 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Dugan Haley L.¹^ORCID,Guthmiller Jenna J.²^ORCID,Arevalo Philip³,Huang Min²,Chen Yao-Qing²,Neu Karlynn E.¹^ORCID,Henry Carole²,Zheng Nai-Ying²,Lan Linda Yu-Ling¹^ORCID,Tepora Micah E.²,Stovicek Olivia²^ORCID,Bitar Dalia²,Palm Anna-Karin E.²^ORCID,Stamper Christopher T.¹^ORCID,Changrob Siriruk²^ORCID,Utset Henry A.²^ORCID,Coughlan Lynda⁴^ORCID,Krammer Florian⁴^ORCID,Cobey Sarah³^ORCID,Wilson Patrick C.¹²^ORCID

Affiliation:

1. Committee on Immunology, University of Chicago, Chicago, IL 60637, USA.

2. Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL 60637, USA.

3. Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA.

4. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Abstract

Antibody immunodominance to conserved influenza virus epitopes is affected by both preexisting B cell memory and route of exposure.

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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