Stereotypic neutralizing V H antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals

Author:

Kim Sang Il12ORCID,Noh Jinsung3ORCID,Kim Sujeong14ORCID,Choi Younggeun1ORCID,Yoo Duck Kyun124ORCID,Lee Yonghee3ORCID,Lee Hyunho3ORCID,Jung Jongtak5,Kang Chang Kyung5,Song Kyoung-Ho5ORCID,Choe Pyoeng Gyun5ORCID,Kim Hong Bin5ORCID,Kim Eu Suk5ORCID,Kim Nam-Joong5ORCID,Seong Moon-Woo6,Park Wan Beom5ORCID,Oh Myoung-don5ORCID,Kwon Sunghoon378910ORCID,Chung Junho1411ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.

2. Ischemic/Hypoxic Disease Institute, Seoul National University Medical Research Center, Seoul 03080, Republic of Korea.

3. Department of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea.

4. Department of Biomedical Science, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.

5. Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.

6. Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.

7. Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea.

8. BK21+ Creative Research Engineer Development for IT, Seoul National University, Seoul 08826, Republic of Korea.

9. Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, Republic of Korea.

10. Institutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Republic of Korea.

11. Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.

Abstract

Stereotypic neutralizing antibody clonotypes specific for SARS-CoV-2 receptor binding domain in patients with COVID-19 and healthy individuals.

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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