Companion animals: Translational scientist’s new best friends

Author:

Kol Amir1,Arzi Boaz2,Athanasiou Kyriacos A.34,Farmer Diana L.5,Nolta Jan A.67,Rebhun Robert B.2,Chen Xinbin27,Griffiths Leigh G.8,Verstraete Frank J. M.2,Murphy Christopher J.29,Borjesson Dori L.1

Affiliation:

1. Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.

2. Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.

3. Department of Biomedical Engineering, University of California, Davis, Davis, CA 95616, U.S.A.

4. Department of Orthopedic Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

5. Department of Surgery, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

6. Department of Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

7. Department of Internal Medicine, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

8. Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.

9. Department of Ophthalmology and Vision Science, School of Medicine, University of California, Davis, Davis, CA 95616, USA.

Abstract

Naturally occurring diseases in companion animals represent an underused resource that holds promise for providing predictive proof of efficacy in the evaluation of new therapeutics and devices.

Funder

NIH

CIRM

ARCS Foundation

UC Davis School of Veterinary Medicine

Winn Foundation

U.C. Davis Stem Cells

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference65 articles.

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4. Code of Federal Regulations - Title 21 - Food and Drugs. 312.23 (a)(8) (2015). www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=312.23.

5. Guidance for industry: Preclinical assessment of investigational cellular and gene therapy products (FDA Center for Biologics Evaluation and Research Washington DC 2013).

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