Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity-Reference-Cited by-同舟云学术

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

Published:2015-09-09 Issue:304 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Modhiran Naphak¹,Watterson Daniel¹²,Muller David A.¹³,Panetta Adele K.¹,Sester David P.¹,Liu Lidong¹,Hume David A.²,Stacey Katryn J.¹²,Young Paul R.¹²

Affiliation:

1. Australian Infectious Diseases Research Centre, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.

2. Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

3. Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Queensland 4072, Australia.

Abstract

Dengue virus NS1 protein induces inflammatory responses via TLR4 and disrupts endothelial cell monolayer integrity.

Funder

Australian Research Council

National Health and Medical Research Council (NHMRC)

NHMRC

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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4. Dengue

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