Ultrasound-mediated gastrointestinal drug delivery

Author:

Schoellhammer Carl M.12,Schroeder Avi123,Maa Ruby1,Lauwers Gregory Yves4,Swiston Albert1,Zervas Michael5,Barman Ross2,DiCiccio Angela M.2,Brugge William R.6,Anderson Daniel G.1278,Blankschtein Daniel1,Langer Robert1278,Traverso Giovanni126

Affiliation:

1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Faculty of Chemical Engineering, Technion—Israel Institute of Technology, Haifa 32000, Israel.

4. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

5. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

6. Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

7. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

8. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

Ultrasound enables rapid and local delivery of drugs to the gastrointestinal tract for treatment of inflammatory diseases, such as ulcerative colitis.

Funder

NIH

Alexander von Humboldt-Stiftung Foundation

Max Planck Research Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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