Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice-Reference-Cited by-同舟云学术

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

Published:2015-02-18 Issue:275 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Fredman Gabrielle¹,Kamaly Nazila²,Spolitu Stefano¹,Milton Jaclyn¹,Ghorpade Devram¹,Chiasson Raymond¹,Kuriakose George¹,Perretti Mauro³,Farokhzad Omid²,Tabas Ira¹

Affiliation:

1. Departments of Medicine, Pathology & Cell Biology, and Physiology, Columbia University, New York, NY 10032, USA.

2. Laboratory of Nanomedicine and Biomaterials, Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

3. The William Harvey Research Institute, Barts and The London School of Medicine, Charterhouse Square, London EC1M 6BQ, UK.

Abstract

Targeted nanoparticles containing Ac2-26 protect against the progression of advanced atherosclerosis in mice by promoting resolution of inflammation through activating FPR2/ALX on myeloid cells.

Funder

NIH Pathway to Independence K99

NIH

Welcome Trust Programme Grant

Program of Excellence in Nanotechnology (PEN) Award

Barts and The London NIHR Cardiovascular BRU

David Koch-Prostate Cancer Foundation Award in Nanotherapeutics

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference52 articles.