VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans-Reference-Cited by-同舟云学术

VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans

Published:2017-06-21 Issue:395 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Nair Nitya¹²^ORCID,Feng Ningguo¹³,Blum Lisa K.¹²,Sanyal Mrinmoy¹³^ORCID,Ding Siyuan¹³^ORCID,Jiang Baoming⁴^ORCID,Sen Adrish¹³^ORCID,Morton John M.⁵,He Xiao-Song¹³,Robinson William H.¹²³^ORCID,Greenberg Harry B.¹²³^ORCID

Affiliation:

1. Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. VA Palo Alto Health Care System, Palo Alto, CA 94304, USA.

4. National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

5. Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

Individual human VP4- and VP7-binding monoclonal antibodies mediate serotype cross-reactive neutralizing immunity to rotaviruses.

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference46 articles.

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3. B. N. Fields D. M. Knipe P. M. Howley D. E. Griffin in Fields Virology (Wolters Kluwer Health/Lippincott Williams & Wilkins 2013) vol. 2 chap. 45 pp. 1347–1401.

4. Antibody response to serotype-specific and cross-reactive neutralization epitopes on VP4 and VP7 after rotavirus infection or vaccination

5. Structure of Rotavirus Outer-Layer Protein VP7 Bound with a Neutralizing Fab

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