Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia-Reference-Cited by-同舟云学术

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia

Published:2017-09-27 Issue:409 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Yuan Yuping¹²³^ORCID,Alwis Imala¹²³^ORCID,Wu Mike C. L.¹²³,Kaplan Zane¹,Ashworth Katrina¹^ORCID,Bark David¹,Pham Alan⁴,Mcfadyen James¹^ORCID,Schoenwaelder Simone M.¹²^ORCID,Josefsson Emma C.⁵⁶^ORCID,Kile Benjamin T.⁵⁶⁷^ORCID,Jackson Shaun P.¹²³⁸^ORCID

Affiliation:

1. Australian Centre for Blood Diseases, Alfred Medical and Research Education Precinct, Monash University, Melbourne, Victoria 3004, Australia.

2. Heart Research Institute, Newtown, New South Wales 2042, Australia.

3. Charles Perkins Centre, University of Sydney, New South Wales 2006, Australia.

4. Department of Anatomical Pathology, Alfred Hospital, Prahran, Victoria 3181, Australia.

5. Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

6. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

7. Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3168, Australia.

8. Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.

Abstract

Neutrophil macroaggregates induce a distinct arterial-venous thrombotic response in the lung after gut ischemia.

Funder

National Health and Medical Research Council

National Heart Foundation, Australia

Lorenzo and Pamela Galli Charitable Trust

Wheaton Trust

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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