Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure-Reference-Cited by-同舟云学术

Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure

Published:2017-07-26 Issue:400 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Li Ning¹²^ORCID,Hansen Brian J.¹²^ORCID,Csepe Thomas A.¹²,Zhao Jichao³^ORCID,Ignozzi Anthony J.¹²^ORCID,Sul Lidiya V.¹²^ORCID,Zakharkin Stanislav O.¹^ORCID,Kalyanasundaram Anuradha¹²,Davis Jonathan P.¹²,Biesiadecki Brandon J.¹²,Kilic Ahmet²⁴,Janssen Paul M. L.¹²⁵,Mohler Peter J.¹²⁵,Weiss Raul²⁴⁵,Hummel John D.²⁴⁵^ORCID,Fedorov Vadim V.¹²^ORCID

Affiliation:

1. Department of Physiology and Cell Biology, Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

2. Dorothy M. Davis Heart and Lung Research Institute, Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

3. Auckland Bioengineering Institute, University of Auckland, Auckland 1010, New Zealand.

4. Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

5. Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Abstract

Multiple redundant and diverse intranodal pacemakers and conduction pathways allow the human sinoatrial node to robustly maintain cardiac rhythm.

Funder

National Institutes of Health

American Heart Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference50 articles.

1. Molecular Architecture of the Human Sinus Node

2. Human sinoatrial node structure: 3D microanatomy of sinoatrial conduction pathways

3. Conduction barriers and pathways of the sinoatrial pacemaker complex: their role in normal rhythm and atrial arrhythmias

4. The origins of the sinus node pacemaker complex in man: Demonstration of dominant and subsidiary foci

5. Demonstration of a widely distributed atrial pacemaker complex in the human heart.

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