Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity-Reference-Cited by-同舟云学术

Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity

Published:2022-01-12 Issue:627 Volume:14 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lambert Katharina¹^ORCID,Moo Keagan G.¹^ORCID,Arnett Azlann¹,Goel Gautam²^ORCID,Hu Alex²^ORCID,Flynn Kaitlin J.²^ORCID,Speake Cate³^ORCID,Wiedeman Alice E.¹^ORCID,Gersuk Vivian H.²^ORCID,Linsley Peter S.²^ORCID,Greenbaum Carla J.³^ORCID,Long S. Alice¹^ORCID,Partridge Rebecca¹⁴^ORCID,Buckner Jane H.¹^ORCID,Khor Bernard¹^ORCID

Affiliation:

1. Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.

2. Center for Systems Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.

3. Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason, 1201 Ninth Avenue, Seattle, WA 98101, USA.

4. Department of Pediatrics, Virginia Mason Medical Center, 100 N.E. Gilman Blvd., Issaquah, WA 98027, USA.

Abstract

Permutational analysis of the immune system reveals advanced immune aging in individuals with Down syndrome and in individuals with type 1 diabetes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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2. Down syndrome

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5. Quantitative, Phenotypical, and Functional Characterization of Cellular Immunity in Children and Adolescents With Down Syndrome

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