Tadalafil Alleviates Muscle Ischemia in Patients with Becker Muscular Dystrophy-Reference-Cited by-同舟云学术

Tadalafil Alleviates Muscle Ischemia in Patients with Becker Muscular Dystrophy

Published:2012-11-28 Issue:162 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Martin Elizabeth A.¹,Barresi Rita²,Byrne Barry J.³,Tsimerinov Evgeny I.⁴,Scott Bryan L.¹,Walker Ashley E.¹,Gurudevan Swaminatha V.¹,Anene Francine⁵,Elashoff Robert M.⁵⁶,Thomas Gail D.¹,Victor Ronald G.¹

Affiliation:

1. The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

2. NSCT Diagnostic & Advisory Service for Rare Neuromuscular Diseases, Institute of Genetic Medicine, Newcastle upon Tyne NE2 4AZ, UK.

3. Powell Gene Therapy Center, University of Florida, Gainesville, FL 32610, USA.

4. Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

5. Department of Biomathematics, University of California, Los Angeles Graduate Division, Los Angeles, CA 90095, USA.

6. Department of Biostatistics, School of Public Health, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

The phosphodiesterase 5A inhibitor tadalafil restores normal blood flow regulation in exercising skeletal muscle of patients with Becker muscular dystrophy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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