Broadly neutralizing antibodies abrogate established hepatitis C virus infection-Reference-Cited by-同舟云学术

Broadly neutralizing antibodies abrogate established hepatitis C virus infection

Published:2014-09-17 Issue:254 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

de Jong Ype P.¹²,Dorner Marcus²,Mommersteeg Michiel C.²,Xiao Jing W.²,Balazs Alejandro B.³,Robbins Justin B.⁴,Winer Benjamin Y.⁵,Gerges Sherif⁵,Vega Kevin²,Labitt Rachael N.²,Donovan Bridget M.²,Giang Erick⁴,Krishnan Anuradha⁶,Chiriboga Luis⁷,Charlton Michael R.⁶,Burton Dennis R.³⁴,Baltimore David⁸,Law Mansun⁴,Rice Charles M.²,Ploss Alexander²⁵

Affiliation:

1. Center for the Study of Hepatitis C, Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, NY 10065, USA.

2. Center for the Study of Hepatitis C, Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

3. Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.

4. Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.

5. Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

6. Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

7. Department of Pathology, New York University Medical Center, New York, NY 10016, USA.

8. Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

HCV-specific neutralizing antibodies protect humanized mice from challenge and suppress established infections.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference52 articles.

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4. Humoral Immune Response in Acute Hepatitis C Virus Infection

5. Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

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