Differential Metabolic Impact of Gastric Bypass Surgery Versus Dietary Intervention in Obese Diabetic Subjects Despite Identical Weight Loss

Author:

Laferrère Blandine12,Reilly David1,Arias Sara1,Swerdlow Nicholas1,Gorroochurn Prakash23,Bawa Baani1,Bose Mousumi1,Teixeira Julio24,Stevens Robert D.56,Wenner Brett R.5,Bain James R.56,Muehlbauer Michael J.5,Haqq Andrea5,Lien Lillian56,Shah Svati H.56,Svetkey Laura P.56,Newgard Christopher B.567

Affiliation:

1. New York Obesity Nutrition Research Center, St. Luke’s Roosevelt Hospital Center, New York, NY 10025, USA.

2. Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

3. Department of Biostatistics, Columbia University, New York, NY 10032, USA.

4. Division of Minimally Invasive Surgery, St. Luke’s Roosevelt Hospital Center, New York, NY 10025, USA.

5. Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27704, USA.

6. Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

7. Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

Abstract

The enhanced decrease in circulating branched-chain amino acids and their metabolites after gastric bypass occurs by mechanisms other than weight loss.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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