A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules-Reference-Cited by-同舟云学术

A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules

Published:2013-10-16 Issue:207 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Li Xiao-jun¹,Hayward Clive¹,Fong Pui-Yee¹,Dominguez Michel¹,Hunsucker Stephen W.¹,Lee Lik Wee¹,McLean Matthew¹,Law Scott¹,Butler Heather¹,Schirm Michael²,Gingras Olivier²,Lamontagne Julie²,Allard Rene²,Chelsky Daniel²,Price Nathan D.³,Lam Stephen⁴,Massion Pierre P.⁵⁶,Pass Harvey⁷,Rom William N.⁸,Vachani Anil⁹,Fang Kenneth C.¹,Hood Leroy³,Kearney Paul¹

Affiliation:

1. Integrated Diagnostics, Seattle, WA 98109, USA.

2. Caprion Proteomics, Montreal, Quebec, H2X 3Y7 Canada.

3. Institute for Systems Biology, Seattle, WA 98109, USA.

4. Department of Pulmonary Medicine, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E6, Canada.

5. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

6. Thoracic Oncology Center, Vanderbilt Ingram Comprehensive Cancer Center, Nashville, TN 37232, USA.

7. Department of Cardiothoracic Surgery, New York University Langone Medical Center, New York, NY 10016, USA.

8. Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.

9. Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Abstract

Systems biology and targeted mass spectrometry were combined to develop and validate a blood-based protein classifier for pulmonary nodules.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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