Intermittent Prophylaxis with Oral Truvada Protects Macaques from Rectal SHIV Infection-Reference-Cited by-同舟云学术

Intermittent Prophylaxis with Oral Truvada Protects Macaques from Rectal SHIV Infection

Published:2010-01-13 Issue:14 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

García-Lerma J. Gerardo¹,Cong Mian-er¹,Mitchell James¹,Youngpairoj Ae S.¹,Zheng Qi¹,Masciotra Silvina¹,Martin Amy¹,Kuklenyik Zsuzsanna²,Holder Angela¹,Lipscomb Jonathan¹,Pau Chou-Pong¹,Barr John R.²,Hanson Debra L.¹,Otten Ron¹,Paxton Lynn¹,Folks Thomas M.¹³,Heneine Walid¹

Affiliation:

1. Division of HIV/AIDS Prevention, National Center for HIV, Hepatitis, STD, and Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA.

2. Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

3. Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, TX 78245, USA.

Abstract

Treating monkeys with single doses of an antiretroviral drug before and after exposure to SHIV provides protection against infection, a schedule that may prove practical in humans.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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