Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy-Reference-Cited by-同舟云学术

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

Published:2012-03-07 Issue:124 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lee Changhan¹,Raffaghello Lizzia²,Brandhorst Sebastian¹³,Safdie Fernando M.¹,Bianchi Giovanna²,Martin-Montalvo Alejandro⁴,Pistoia Vito²,Wei Min¹,Hwang Saewon¹,Merlino Annalisa¹,Emionite Laura⁵,de Cabo Rafael⁴,Longo Valter D.¹

Affiliation:

1. Andrus Gerontology Center, Department of Biological Sciences and Norris Cancer Center, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089–0191, USA.

2. Laboratory of Oncology, Giannina Gaslini Institute, Genova 16145, Italy.

3. Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen 45117, Germany.

4. Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

5. Animal Research Facility Istituto Tumori, Genova 16145, Italy.

Abstract

Short-term starvation increases the effectiveness of chemotherapy against a wide range of tumor cell types.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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