Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice

Author:

Silva Carla G.123,Métin Christine45,Fazeli Walid6,Machado Nuno J.3,Darmopil Sanja127,Launay Pierre-Serge45,Ghestem Antoine12,Nesa Marie-Pascale12,Bassot Emilie12,Szabó Eszter3,Baqi Younis8,Müller Christa E.8,Tomé Angelo R.39,Ivanov Anton12,Isbrandt Dirk6,Zilberter Yuri12,Cunha Rodrigo A.310,Esclapez Monique12,Bernard Christophe12

Affiliation:

1. Aix Marseille Université, INS, 13005 Marseille, France.

2. Inserm, UMR_S 1106, 13005 Marseille, France.

3. Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.

4. INSERM UMR-S 839, Institut du Fer à Moulin, 75005 Paris, France.

5. Université Pierre et Marie Curie, 75005 Paris, France.

6. Experimental Neuropediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

7. Department of Anatomy, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.

8. PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, Pharmaceutical Sciences Bonn, University of Bonn, 53121 Bonn, Germany.

9. Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, 3030-790 Coimbra, Portugal.

10. Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.

Abstract

Exposure to adenosine receptor antagonists in utero affects fetal brain development in mice.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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