Parallel Discovery of Alzheimer’s Therapeutics

Author:

Lo Andrew W.123,Ho Carole4,Cummings Jayna1,Kosik Kenneth S.5

Affiliation:

1. Massachusetts Institute of Technology (MIT) Sloan School of Management and Laboratory for Financial Engineering, Cambridge, MA 02142, USA.

2. MIT Computer Science and Artificial Intelligence Laboratory and Department of Electrical Engineering and Computer Science, Cambridge, MA 02142, USA.

3. AlphaSimplex Group, Cambridge, MA 02142, USA.

4. Early Clinical Development, Genentech, South San Francisco, CA 94080, USA.

5. Neuroscience Research Institute and Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

Abstract

Government support for parallel development of AD therapeutics.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference33 articles.

1. 2014 Alzheimer's disease facts and figures

2. Pharmaceutical Research and Manufacturers of America (PhRMA) Researching Alzheimer’s Medicines: Setbacks and Stepping Stones (PhRMA Washington DC 2012).

3. Johnson & Johnson “Johnson & Johnson Announces Discontinuation of Phase 3 Development of Bapineuzumab Intravenous (IV) in Mild-to-Moderate Alzheimer’s Disease ” published online 06 August 2012.www.investor.jnj.com/releasedetail.cfm?ReleaseID=698466.

4. Eli Lilly “Eli Lilly and Company Announces Top-Line Results on Solanezumab Phase 3 Clinical Trials in Patients with Alzheimer’s Disease ” published online 24 August 2012.http://lilly.mediaroom.com/index.php?s=9042&item=132129.

5. Commercializing biomedical research through securitization techniques

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