PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis

Author:

Coleman M. Teresa1,Chen Ray Y.2,Lee Myungsun3,Lin Philana Ling4,Dodd Lori E.5,Maiello Pauline1,Via Laura E.2,Kim Youngran3,Marriner Gwendolyn2,Dartois Veronique6,Scanga Charles1,Janssen Christopher7,Wang Jing8,Klein Edwin7,Cho Sang Nae39,Barry Clifton E.210,Flynn JoAnne L.1

Affiliation:

1. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.

2. Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

3. International Tuberculosis Research Center, Changwon 631-710, Republic of Korea.

4. Department of Pediatrics, Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA 15260, USA.

5. Biostatistics Research Branch, NIAID, NIH, Bethesda, MD 20892, USA.

6. Public Health Research Institute Center, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.

7. Division of Laboratory Animal Resources, University of Pittsburgh, Pittsburgh, PA 15260, USA.

8. Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.

9. Department of Microbiology, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea.

10. Institute of Infectious Disease and Molecular Medicine, and the Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch 7701, South Africa.

Abstract

PET/CT imaging in macaques and humans with TB shows a beneficial therapeutic response to linezolid and a new oxazolidinone antibiotic, AZD5847.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3