Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis-Reference-Cited by-同舟云学术

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis

Published:2011-03-23 Issue:75 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Fang Fang¹,Turcan Sevin¹,Rimner Andreas²,Kaufman Andrew¹,Giri Dilip³,Morris Luc G. T.¹⁴,Shen Ronglai⁵,Seshan Venkatraman⁵,Mo Qianxing⁵,Heguy Adriana¹,Baylin Stephen B.⁶,Ahuja Nita⁶,Viale Agnes⁷,Massague Joan⁸,Norton Larry⁹,Vahdat Linda T.¹⁰,Moynahan Mary Ellen⁹,Chan Timothy A.¹²

Affiliation:

1. Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

2. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

3. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

4. Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

5. Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

6. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Suite 544, Baltimore, MD 21231, USA.

7. Genomics Core, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

8. Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

9. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

10. Department of Medicine, Weill Cornell Medical Center, 425 East 61st Street, New York, NY 10065, USA.

Abstract

Breast cancer methylomes contribute to metastatic potential, modulate the metastasis transcriptome, and predict disease outcome.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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