CD44-SLC1A2 Gene Fusions in Gastric Cancer

Author:

Tao Jiong12,Deng Nian Tao2,Ramnarayanan Kalpana3,Huang Baohua1,Oh Hue Kian3,Leong Siew Hong4,Lim Seong Soo5,Tan Iain Beehuat26,Ooi Chia Huey2,Wu Jeanie3,Lee Minghui3,Zhang Shenli2,Rha Sun Young7,Chung Hyun Cheol7,Smoot Duane T.8,Ashktorab Hassan8,Kon Oi Lian4,Cacheux Valere5,Yap Celestial1,Palanisamy Nallasivam5,Tan Patrick12359

Affiliation:

1. Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.

2. Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857, Singapore.

3. Cellular and Molecular Research, National Cancer Centre of Singapore, 11 Hospital Drive, Singapore 169610, Singapore.

4. Division of Medical Sciences, National Cancer Centre of Singapore, Singapore 169610, Singapore.

5. Genome Institute of Singapore, 60 Biopolis Street, Genome 02-01, Singapore 138672, Singapore.

6. Division of Medical Oncology, National Cancer Centre of Singapore, Singapore 169610, Singapore.

7. Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 134 Shinchon-Dong, Seodaemun-Ku, Seoul 120-752, South Korea.

8. Department of Medicine and Cancer Center, Howard University College of Medicine, 2041 Georgia Avenue, Washington, DC 20060, USA.

9. Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119074, Singapore.

Abstract

One partner of a fusion gene found in gastric cancer, CD44-SLC1A2 , may contribute to the tumor’s abnormal metabolism.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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