Genital HIV-1 RNA Predicts Risk of Heterosexual HIV-1 Transmission

Author:

Baeten Jared M.123,Kahle Erin13,Lingappa Jairam R.124,Coombs Robert W.25,Delany-Moretlwe Sinead6,Nakku-Joloba Edith7,Mugo Nelly R.18,Wald Anna2359,Corey Lawrence2359,Donnell Deborah110,Campbell Mary S.2,Mullins James I.25,Celum Connie123

Affiliation:

1. Department of Global Health, University of Washington, Seattle, WA 98195, USA.

2. Department of Medicine, University of Washington, Seattle, WA 98195, USA.

3. Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.

4. Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.

5. Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.

6. Wits Institute for Reproductive Health and HIV, University of the Witwatersrand, Johannesburg 2001, South Africa.

7. Department of Epidemiology and Biostatistics, Makerere University, Kampala, Uganda.

8. Department of Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya.

9. Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

10. Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Abstract

Genital HIV-1 RNA quantity predicts risk of heterosexual HIV-1 transmission independently of plasma HIV-1 concentration.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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