Proteins Required for Centrosome Clustering in Cancer Cells-Reference-Cited by-同舟云学术

Proteins Required for Centrosome Clustering in Cancer Cells

Published:2010-05-26 Issue:33 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Leber Blanka¹,Maier Bettina¹,Fuchs Florian²,Chi Jing¹,Riffel Phillip¹,Anderhub Simon¹,Wagner Ludmila¹,Ho Anthony D.³,Salisbury Jeffrey L.⁴,Boutros Michael²,Krämer Alwin¹

Affiliation:

1. Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.

2. Division of Signaling and Functional Genomics, German Cancer Research Center and University of Heidelberg, Medical Faculty Mannheim, 69120 Heidelberg, Germany.

3. Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.

4. Tumor Biology Program and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.

Abstract

Identified in an RNA interference screen, proteins that prevent spindle multipolarity in human cancer cells may prove to be promising drug targets.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference52 articles.

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5. Centrosome aberrations: cause or consequence of cancer progression?

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