Metabolic Signatures of Exercise in Human Plasma-Reference-Cited by-同舟云学术

Metabolic Signatures of Exercise in Human Plasma

Published:2010-05-26 Issue:33 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lewis Gregory D.¹²³⁴,Farrell Laurie¹,Wood Malissa J.¹,Martinovic Maryann¹,Arany Zoltan⁵,Rowe Glenn C.⁵,Souza Amanda⁴,Cheng Susan¹⁶⁷,McCabe Elizabeth L.⁶,Yang Elaine⁴,Shi Xu⁴,Deo Rahul¹⁸,Roth Frederick P.⁸,Asnani Aarti¹²,Rhee Eugene P.⁴⁹,Systrom David M.¹⁰,Semigran Marc J.¹,Vasan Ramachandran S.⁶¹¹¹²,Carr Steven A.⁴,Wang Thomas J.¹⁶,Sabatine Marc S.³⁷,Clish Clary B.⁴,Gerszten Robert E.¹²³⁴

Affiliation:

1. Cardiology Division and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.

2. Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

3. Donald W. Reynolds Cardiovascular Clinical Research Center on Atherosclerosis at Harvard Medical School, Boston, MA 02115, USA.

4. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

5. Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

6. Framingham Heart Study, Framingham, MA 01702, USA.

7. Cardiovascular Division, Brigham and Women’s Hospital, Boston, MA 02115, USA.

8. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

9. Nephrology Division, Massachusetts General Hospital, Boston, MA 02114, USA.

10. Pulmonary and Critical Care Division, Massachusetts General Hospital, Boston, MA 02114, USA.

11. Sections of Epidemiology and Preventive Medicine, Boston University School of Medicine, Boston, MA 02118, USA.

12. Cardiology Section, Boston University School of Medicine, Boston, MA 02118, USA.

Abstract

Measurement by mass spectrometry of 200 blood metabolites reveals that individuals who are more fit respond more effectively to exercise, as shown by larger exercise-induced increase in glycerol.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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