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Wnt Proteins Promote Bone Regeneration

Published:2010-04-28 Issue:29 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Minear Steven¹,Leucht Philipp¹²,Jiang Jie¹,Liu Bo¹,Zeng Arial³,Fuerer Christophe³,Nusse Roel³,Helms Jill A.¹

Affiliation:

1. Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford School of Medicine, Stanford, CA 94305, USA.

2. Department of Orthopaedic Surgery, Stanford School of Medicine, Stanford, CA 94305, USA.

3. Howard Hughes Medical Institute, Department of Developmental Biology, Stanford School of Medicine, Stanford, CA 94305, USA.

Abstract

A liposome-encased ligand for the Wnt signaling pathway can accelerate bone regeneration after injury.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference60 articles.

1. Stem Cells and Their Niches

2. Translating insights from development into regenerative medicine: The function of Wnts in bone biology

3. Wnt proteins are lipid-modified and can act as stem cell growth factors

4. Monounsaturated Fatty Acid Modification of Wnt Protein: Its Role in Wnt Secretion

5. Bone Regeneration Is Regulated by Wnt Signaling

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