Balancing Tissue and Tumor Formation in Regenerative Medicine

Author:

Bailey Alexander M.1

Affiliation:

1. Office of Cellular, Tissue, and Gene Therapies, Center for Biologics Evaluation and Research, FDA, Rockville, MD 20852, USA.

Abstract

A set of general principles can guide preclinical testing strategies for evaluating the tumorigenicity of regenerative medicine products.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference9 articles.

1. Embryonic Stem Cell Lines Derived from Human Blastocysts

2. Setting Standards for Human Embryonic Stem Cells

3. What Is the Oncologic Risk of Stem Cell Treatment for Heart Disease?

4. Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis

5. Points to Consider in the Characterization of Cell Lines Used to Produce Biologicals Center for Biologics Evaluation and Research (CBER) FDA (1993). http://www.fda.gov/downloads/biologicsbloodvaccines/safetyavailability/ucm162863.pdf.

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