A Translational Paradigm for the Preclinical Evaluation of the Stroke Neuroprotectant Tat-NR2B9c in Gyrencephalic Nonhuman Primates-Reference-Cited by-同舟云学术

A Translational Paradigm for the Preclinical Evaluation of the Stroke Neuroprotectant Tat-NR2B9c in Gyrencephalic Nonhuman Primates

Author:

Cook Douglas J.¹,Teves Lucy¹,Tymianski Michael¹²³⁴

Affiliation:

1. Toronto Western Hospital Research Institute, Toronto, Ontario M5T 2S8, Canada.

2. Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

3. Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

4. Department of Surgery, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Abstract

Nonhuman primates treated with a neuroprotectant after stroke showed outcomes that correctly anticipated those of a corresponding human trial.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference32 articles.

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