IL-29 Is Produced by T H 17 Cells and Mediates the Cutaneous Antiviral Competence in Psoriasis-Reference-Cited by-同舟云学术

IL-29 Is Produced by T H 17 Cells and Mediates the Cutaneous Antiviral Competence in Psoriasis

Published:2013-09-25 Issue:204 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Wolk Kerstin¹²³,Witte Katrin¹²,Witte Ellen¹²,Raftery Martin⁴,Kokolakis Georgios¹²,Philipp Sandra¹²,Schönrich Günther⁴,Warszawska Katarzyna¹,Kirsch Stefan¹,Prösch Susanna⁴,Sterry Wolfram⁵,Volk Hans-Dieter⁶⁷,Sabat Robert¹²³

Affiliation:

1. Interdisciplinary Group of Molecular Immunopathology, Dermatology/Medical Immunology, University Hospital Charité, 10117 Berlin, Germany.

2. Psoriasis Research and Treatment Center, University Hospital Charité, 10117 Berlin, Germany.

3. Research Center Immunosciences, University Hospital Charité, 10117 Berlin, Germany.

4. Institute of Virology, University Hospital Charité, Berlin 10117, Germany.

5. Department of Dermatology and Allergy, University Hospital Charité, 10117 Berlin, Germany.

6. Institute of Medical Immunology, University Hospital Charité, 10117 Berlin, Germany.

7. Berlin-Brandenburg Center of Regenerative Therapies, University Hospital Charité, 10117 Berlin, Germany.

Abstract

Psoriasis, but not atopic dermatitis patients, express elevated antiviral proteins in lesional skin because of the T H 17 cytokine IL-29.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

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2. Psoriasis

3. Psoriasis

4. Contrasting pathogenesis of atopic dermatitis and psoriasis—Part II: Immune cell subsets and therapeutic concepts

5. Chapter 3 Cellular and Molecular Mechanisms in Atopic Dermatitis

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