Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

Author:

Jiang Liwei1,Wang Nianshuang2,Zuo Teng13,Shi Xuanling1,Poon Kwok-Man Vincent4,Wu Yongkang5,Gao Fei1,Li Danyang1,Wang Ruoke1,Guo Jianying1,Fu Lili1,Yuen Kwok-Yung4,Zheng Bo-Jian4,Wang Xinquan2,Zhang Linqi1

Affiliation:

1. Comprehensive AIDS Research Center, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, China.

2. Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.

3. School of Life Sciences, Tsinghua University, Beijing 100084, China.

4. Department of Microbiology, The University of Hong Kong, Hong Kong, China.

5. Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.

Abstract

Human neutralizing monoclonal antibody could serve as a therapeutic intervention against MERS-CoV infection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

1. Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic;Chan J. F.;65,2012

2. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012

3. Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group

4. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

5. State of knowledge and data gaps of Middle East respiratory syndrome coronavirus (MERS-CoV) in humans.;The WHO MERS-CoV Research Group;PLOS Curr.,2013

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3