Magnetic Resonance of 2-Hydroxyglutarate in IDH1 -Mutated Low-Grade Gliomas-Reference-Cited by-同舟云学术

Magnetic Resonance of 2-Hydroxyglutarate in IDH1 -Mutated Low-Grade Gliomas

Published:2012-01-11 Issue:116 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Elkhaled Adam¹,Jalbert Llewellyn E.²,Phillips Joanna J.³⁴,Yoshihara Hikari A. I.¹,Parvataneni Rupa¹⁴,Srinivasan Radhika¹,Bourne Gabriela¹,Berger Mitchel S.⁴,Chang Susan M.⁴,Cha Soonmee¹,Nelson Sarah J.¹²

Affiliation:

1. Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA.

2. Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94158, USA.

3. Department of Pathology, University of California, San Francisco, San Francisco, CA 94158, USA.

4. Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA.

Abstract

2-Hydroxyglutarate can be detected ex vivo in biopsy tissue from IDH1 -mutant low-grade gliomas with proton high-resolution magic angle spinning NMR spectroscopy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference33 articles.

1. Low-Grade Gliomas in Adults

2. Molecular neuropathology of low-grade gliomas and its clinical impact

3. IDH1andIDH2Mutations in Gliomas

4. An Integrated Genomic Analysis of Human Glioblastoma Multiforme

5. IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas

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