Carbamylation of Serum Albumin as a Risk Factor for Mortality in Patients with Kidney Failure

Author:

Berg Anders H.1,Drechsler Christiane2,Wenger Julia3,Buccafusca Roberto45,Hod Tammy4,Kalim Sahir3,Ramma Wenda1,Parikh Samir M.4,Steen Hanno5,Friedman David J.4,Danziger John4,Wanner Christoph2,Thadhani Ravi3,Karumanchi S. Ananth46

Affiliation:

1. Division of Clinical Chemistry, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

2. Division of Nephrology, Department of Internal Medicine, University of Würzburg, Würzburg D-97074, Germany.

3. Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

4. Division of Nephrology and Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.

5. Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

6. Howard Hughes Medical Institute, Boston, MA 02215, USA.

Abstract

Increased carbamylation of serum albumin is associated with increased mortality in patients with kidney failure.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference54 articles.

1. The burden of kidney disease: Improving global outcomes

2. Clinical epidemiology of cardiovascular disease in chronic renal disease

3. United States Renal Data System 2009 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease (National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases Bethesda MD 2009).

4. Atorvastatin in Patients with Type 2 Diabetes Mellitus Undergoing Hemodialysis

5. Rosuvastatin and Cardiovascular Events in Patients Undergoing Hemodialysis

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