Long-Term Remissions of Severe Pemphigus After Rituximab Therapy Are Associated with Prolonged Failure of Desmoglein B Cell Response-Reference-Cited by-同舟云学术

Long-Term Remissions of Severe Pemphigus After Rituximab Therapy Are Associated with Prolonged Failure of Desmoglein B Cell Response

Published:2013-03-06 Issue:175 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Colliou Natacha¹,Picard Damien¹,Caillot Frédérique¹,Calbo Sébastien¹,Le Corre Stéphanie²,Lim Annick³,Lemercier Brigitte³,Le Mauff Brigitte⁴,Maho-Vaillant Maud¹,Jacquot Serge²,Bedane Christophe⁵,Bernard Philippe⁶,Caux Frédéric⁷,Prost Catherine⁷,Delaporte Emmanuel⁸,Doutre Marie-Sylvie⁹,Dreno Brigitte¹⁰,Franck Nathalie¹¹,Ingen-Housz-Oro Saskia¹²,Chosidow Olivier¹²,Pauwels Christine¹³,Picard Catherine¹⁴,Roujeau Jean-Claude¹²,Sigal Michèle¹⁵,Tancrede-Bohin Emmanuelle¹⁶,Templier Isabelle¹⁷,Eming Rüdiger¹⁸,Hertl Michael¹⁸,D’Incan Michel¹⁹,Joly Pascal¹,Musette Philippe¹

Affiliation:

1. Department of Dermatology, Inserm U905, Institute for Research and Innovation in Biomedicine, Rouen University Hospital, University of Normandy, Rouen 76031, France.

2. Inserm U905, Institute for Research and Innovation in Biomedicine, University of Normandy, Rouen 76031, France.

3. Antiviral Immunity, Biotherapy and Vaccine Unit, Institut Pasteur, Inserm, U668, Paris 75724, France.

4. Department of Immunology and Immunopathology, Caen University Hospital, Caen 14033, France.

5. Department of Dermatology, Limoges University Hospital, Limoges 87042, France.

6. Department of Dermatology, Reims University Hospital, Reims 51092, France.

7. Department of Dermatology, Paris XIII University Hospital, AP-HP, Bobigny 93009, France.

8. Department of Dermatology, Lille University Hospital, Lille 59037, France.

9. Department of Dermatology, Pessac Haut Leveque University Hospital, Bordeaux 33604, France.

10. Department of Dermatology, Nantes University Hospital, Nantes 44093, France.

11. Department of Dermatology, Cochin University Hospital, AP-HP, Paris 75014, France.

12. Department of Dermatology, Henri Mondor University Hospital, AP-HP, Créteil 94000, France.

13. Department of Dermatology, CHI Poissy/Saint-Germain-en-Laye, Saint-Germain-en Laye 78100, France.

14. Department of Dermatology, Bichat University Hospital, AP-HP, Paris 75877, France.

15. Department of Dermatology, Victor Dupouy Hospital, Argenteuil 95107, France.

16. Department of Dermatology, Saint Louis University Hospital, AP-HP, Paris 75010, France.

17. Department of Dermatology, Grenoble University Hospital, Grenoble 38043, France.

18. Faculty of Medicine, Philipp University, Marburg 35037, Germany.

19. Department of Dermatology, Clermont-Ferrand University Hospital, Clermont-Ferrand 63003, France.

Abstract

Changes in the B cell repertoire mediate long-lasting therapeutic effects of rituximab in pemphigus patients.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference42 articles.

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2. M. Amagai in Dermatology J. L. Bolognia J. L. Jorizzo R. P. Rapini Eds. (Mosby Elsevier Toronto 2008).

3. Bullous pemphigoid and pemphigus vulgaris--incidence and mortality in the UK: population based cohort study

4. Human autoantibodies against a desmosomal protein complex with a calcium-sensitive epitope are characteristic of pemphigus foliaceus patients.

5. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

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