Circulating Cell-Free DNA Enables Noninvasive Diagnosis of Heart Transplant Rejection-Reference-Cited by-同舟云学术

Circulating Cell-Free DNA Enables Noninvasive Diagnosis of Heart Transplant Rejection

Published:2014-06-18 Issue:241 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

De Vlaminck Iwijn¹²,Valantine Hannah A.³,Snyder Thomas M.¹²,Strehl Calvin³,Cohen Garrett³,Luikart Helen³,Neff Norma F.¹²,Okamoto Jennifer¹²,Bernstein Daniel⁴,Weisshaar Dana⁵,Quake Stephen R.¹²,Khush Kiran K.³

Affiliation:

1. Departments of Bioengineering and Applied Physics, Stanford University, Stanford, CA 94305, USA.

2. Howard Hughes Medical Institute, Stanford, CA 94305, USA.

3. Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

4. Department of Pediatrics (Cardiology), Stanford University and the Stanford Cardiovascular Research Institute, Stanford, CA 94305, USA.

5. Office of Heart Transplant Services, Kaiser Permanente Northern California, Santa Clara Medical Center, Santa Clara, CA 95051, USA.

Abstract

In a prospective cohort study of heart transplant recipients, sequencing-based quantification of donor-derived DNA in plasma of recipients noninvasively diagnosed transplant rejection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference24 articles.

1. Complications of Endomyocardial Biopsy in Heart Transplant Patients: A Retrospective Study of 2117 Consecutive Procedures

2. Nodular Endocardial Infiltrates (Quilty Lesions) Cause Significant Variability in Diagnosis of ISHLT Grade 2 and 3A Rejection in Cardiac Allograft Recipients

3. Presence of Donor- and Recipient-derived DNA in Cell-free Urine Samples of Renal Transplantation Recipients: Urinary DNA Chimerism

4. Presence of donor-specific DNA in plasma of kidney and liver-transplant recipients

5. Cell-free DNA as a measure of transplant injury.;Sigdel T. K.;Clin. Transpl.,2012

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