Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis

Author:

Sampson Erik R.1,Hilton Matthew J.1,Tian Ye1,Chen Di1,Schwarz Edward M.1,Mooney Robert A.2,Bukata Susan V.1,O’Keefe Regis J.1,Awad Hani3,Puzas J. Edward1,Rosier Randy N.1,Zuscik Michael J.1

Affiliation:

1. Department of Orthopaedics and Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.

2. Department of Pathology and Laboratory Medicine, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.

3. Department of Biomedical Engineering, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.

Abstract

Teriparatide is chondroprotective and chondroregenerative in a mouse model of injury-induced osteoarthritis of the knee.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference84 articles.

1. Prevalence and most common causes of disability among adults—United States, 2005;Centers for Disease Control and Prevention (CDC);MMWR Morb. Mortal. Wkly. Rep.,2009

2. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I

3. Projections of US prevalence of arthritis and associated activity limitations

4. Osteoarthritis of the Knee

5. Osteoarthritis: A tale of three tissues;Samuels J.;Bull. NYU Hosp. Jt. Dis.,2008

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