Computational Genetic Mapping in Mice: The Ship Has Sailed-Reference-Cited by-同舟云学术

Computational Genetic Mapping in Mice: The Ship Has Sailed

Published:2009-10-21 Issue:3 Volume:1 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Zheng Ming¹,Shafer Steve²,Liao Guochun³,Liu Hong-Hsing³,Peltz Gary¹

Affiliation:

1. Department of Anesthesia, Stanford University, Stanford, CA, USA.

2. Department of Anesthesiology, Columbia University, New York, NY, USA.

3. Department of Genetics and Genomics, Roche Palo Alto, Palo Alto, CA, USA.

Abstract

Computational haplotype-based genetic mapping can be used to discover new biological mechanisms, disease-related pathways, and unexpected uses for existing drugs. Here we discuss the benefits and limitations of this methodology, its impact on translational medicine, and its future course.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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