A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

Author:

Delville Marianne1,Sigdel Tara K.2,Wei Changli3,Li Jing3,Hsieh Szu-Chuan2,Fornoni Alessia4,Burke George W.5,Bruneval Patrick6,Naesens Maarten7,Jackson Annette8,Alachkar Nada8,Canaud Guillaume1,Legendre Christophe1,Anglicheau Dany1,Reiser Jochen3,Sarwal Minnie M.2

Affiliation:

1. Department of Kidney Transplantation, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Université Paris Descartes Sorbonne Paris Cité, INSERM U1171, Réseau Thématique de Recherche et de Soins Centaure, Labex Transplantex, 75015 Paris, France.

2. Division of Transplant Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

3. Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

4. Peggy and Harold Katz Family Drug Discovery Center, Division of Nephrology and Hypertension, University of Miami School of Medicine, Miami, FL 33146, USA.

5. Division of Transplant Surgery, University of Miami School of Medicine, Miami, FL 33146, USA.

6. Department of Pathology, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France.

7. Nephrology and Renal Transplantation, University Hospitals Leuven, 3000 Leuven, Belgium.

8. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

Abstract

Pretransplant antibodies, particularly anti-CD40, correlate with risk of recurrent focal segmental glomerulosclerosis after kidney transplant.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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