Penetration of Tenofovir and Emtricitabine in Mucosal Tissues: Implications for Prevention of HIV-1 Transmission-Reference-Cited by-同舟云学术

Penetration of Tenofovir and Emtricitabine in Mucosal Tissues: Implications for Prevention of HIV-1 Transmission

Published:2011-12-07 Issue:112 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Patterson Kristine B.¹,Prince Heather A.¹,Kraft Eric²,Jenkins Amanda J.²,Shaheen Nicholas J.¹,Rooney James F.³,Cohen Myron S.¹,Kashuba Angela D. M.²

Affiliation:

1. University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

2. University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC 27599, USA.

3. Gilead Sciences, Foster City, CA 94404, USA.

Abstract

Antiretroviral drugs are found at different concentrations in human cervical, vaginal, and rectal mucosal tissues with implications for designing PrEP trials to prevent HIV transmission.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference33 articles.

1. UNAIDS Report on the Global AIDS Epidemic 2010; http://www.unaids.org/documents/20101123_GlobalReport_em.pdf [accessed 14 December 2010].

2. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis

3. Panel on the Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1 Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States 24 May 2010 pp. 1–117; http://www.aidsinfo.nih.gov/Guidelines/GuidelineDetail.aspx [accessed 14 December 2010].

4. Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

5. Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

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