Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase-Reference-Cited by-同舟云学术

Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase

Author:

García Mayra¹,Cooper Arik¹,Shi Wei¹,Bornmann William²,Carrion Ricardo³,Kalman Daniel⁴,Nabel Gary J.¹

Affiliation:

1. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

2. Organic Chemistry Section, M. D. Anderson Cancer Center, University of Texas, Houston, TX 77030, USA.

3. Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, TX 78227, USA.

4. Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

Abstract

Ebola virus growth is regulated by a c-Abl tyrosine kinase, which modulates the viral protein VP40, and can be blocked by c-Abl antagonists.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference58 articles.

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