Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

Author:

Happle Christine12,Lachmann Nico34,Škuljec Jelena1,Wetzke Martin1,Ackermann Mania34,Brennig Sebastian34,Mucci Adele34,Jirmo Adan Chari12,Groos Stephanie5,Mirenska Anja1,Hennig Christina12,Rodt Thomas6,Bankstahl Jens P.7,Schwerk Nicolaus12,Moritz Thomas34,Hansen Gesine12

Affiliation:

1. Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, 30625 Hannover, Germany.

2. Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), 30625 Hannover, Germany.

3. Reprogramming and Gene Therapy Group, REBIRTH Cluster-of Excellence, Hannover Medical School, 30625 Hannover, Germany.

4. Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.

5. Institute of Cell Biology in the Center of Anatomy, Hannover Medical School, 30625 Hannover, Germany.

6. Department of Diagnostic and Interventional Radiology, Hannover Medical School, 30625 Hannover, Germany.

7. Institute for Preclinical Molecular Imaging, Hannover Medical School, 30625 Hannover, Germany.

Abstract

Macrophage progenitors are an effective and long-lasting therapy of hereditary pulmonary alveolar proteinosis.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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