Establishment of Antitumor Memory in Humans Using in Vitro–Educated CD8 + T Cells-Reference-Cited by-同舟云学术

Establishment of Antitumor Memory in Humans Using in Vitro–Educated CD8 + T Cells

Published:2011-04-27 Issue:80 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Butler Marcus O.¹²³,Friedlander Philip¹²³,Milstein Matthew I.¹,Mooney Mary M.¹,Metzler Genita¹,Murray Andrew P.¹,Tanaka Makito¹²³,Berezovskaya Alla¹,Imataki Osamu¹²³,Drury Linda¹,Brennan Lisa¹,Flavin Marisa¹,Neuberg Donna⁴,Stevenson Kristen⁴,Lawrence Donald³⁵,Hodi F. Stephen¹²³,Velazquez Elsa F.⁶⁷,Jaklitsch Michael T.⁸⁹,Russell Sara E.⁹¹⁰,Mihm Martin¹³¹¹¹²,Nadler Lee M.¹²³,Hirano Naoto¹²³¹³¹⁴

Affiliation:

1. Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.

2. Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.

3. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

4. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

5. Department of Thoracic Surgery, Brigham and Women’s Hospital, Boston, MA 02115, USA.

6. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA.

7. Caris Life Science, Tufts University School of Medicine, Boston, MA 02111, USA.

8. Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

9. Department of Surgery, Harvard Medical School, Boston, MA 02115, USA.

10. Department of Surgery, Brigham and Women’s Hospital, Boston, MA 02115, USA.

11. Department of Dermatology, Brigham and Women’s Hospital, Boston, MA 02115, USA.

12. Department of Dermatology, Harvard Medical School, Boston, MA 02115, USA.

13. Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Ontario, Canada M5G 2M9.

14. University of Toronto, Toronto, Ontario, Canada M5S 1A8.

Abstract

Antitumor CD8 + T cells educated in vitro can persist as memory T cells and induce antitumor responses in humans without prior conditioning or cytokine treatment.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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