A Dendritic Cell–Based Vaccine Elicits T Cell Responses Associated with Control of HIV-1 Replication-Reference-Cited by-同舟云学术

A Dendritic Cell–Based Vaccine Elicits T Cell Responses Associated with Control of HIV-1 Replication

Published:2013-01-02 Issue:166 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

García Felipe¹,Climent Nuria¹,Guardo Alberto C.¹,Gil Cristina¹,León Agathe¹,Autran Brigitte²,Lifson Jeffrey D.³,Martínez-Picado Javier⁴⁵,Dalmau Judit⁴,Clotet Bonaventura⁴,Gatell Josep M.¹,Plana Montserrat¹,Gallart Teresa¹,

Affiliation:

1. Hospital Clinic-IDIBAPS, HIVACAT, University of Barcelona, 08036 Barcelona, Spain.

2. INSERM UMR-S-945, Université Paris-VI Pierre-et-Marie-Curie, Hôpital Pitié-Salpêtrière, 75013 Paris, France.

3. AIDS and Cancer Virus Program, SAIC-Frederick Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

4. AIDS Research Institute IrsiCaixa, Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.

5. Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Spain.

Abstract

Therapeutic DC vaccines elicit HIV-1–specific immune responses that change viral set point in patients of cART.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference31 articles.

1. The Emerging Race to Cure HIV Infections

2. Vigorous HIV-1-Specific CD4 + T Cell Responses Associated with Control of Viremia

3. Immunopathogenesis and immunotherapy in AIDS virus infections

4. Therapeutic vaccines against HIV need international partnerships

5. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

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