1. Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
2. Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
3. Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
4. Department of Genetics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
5. Department of Bioethics, Cleveland Clinic, Cleveland, OH 44195, USA.