Bactericidal/Permeability-Increasing Protein (rBPI 21 ) and Fluoroquinolone Mitigate Radiation-Induced Bone Marrow Aplasia and Death-Reference-Cited by-同舟云学术

Bactericidal/Permeability-Increasing Protein (rBPI 21 ) and Fluoroquinolone Mitigate Radiation-Induced Bone Marrow Aplasia and Death

Published:2011-11-23 Issue:110 Volume:3 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Guinan Eva C.¹²³⁴,Barbon Christine M.⁵,Kalish Leslie A.⁶,Parmar Kalindi¹,Kutok Jeff⁷,Mancuso Christy J.⁸,Stoler-Barak Liat⁸,Suter Eugénie E.⁸,Russell Janice D.¹,Palmer Christine D.⁸,Gallington Leighanne C.⁸,Voskertchian Annie⁵,Vergilio Jo-Anne⁹,Cole Geoffrey⁵,Zhu Kaya¹,D’Andrea Alan¹³,Soiffer Robert⁵¹⁰,Weiss Jerrold P.¹¹,Levy Ofer⁸¹²¹³

Affiliation:

1. Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

2. Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

3. Department of Radiation Oncology, Harvard Medical School, Boston, MA 02115, USA.

4. Division of Hematology/Oncology, Children’s Hospital Boston, Boston, MA 02115, USA.

5. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

6. Clinical Research Program, Children’s Hospital Boston, Boston, MA 02115, USA.

7. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA.

8. Division of Infectious Diseases, Children’s Hospital Boston, Boston, MA 02115, USA.

9. Department of Pathology, Children’s Hospital Boston, Boston, MA 02115, USA.

10. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

11. Inflammation Program and Department of Medicine, University of Iowa, Coralville, IA 52241, USA.

12. Leder Human Biology and Translational Medicine Program, Harvard Medical School, Boston, MA 02115, USA.

13. Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Even when given 24 hours after lethal radiation, a fragment of an endotoxin-neutralizing protein plus a fluoroquinolone antibiotic improves survival and hematopoietic recovery in mice.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference51 articles.

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5. Medical Response to a Nuclear Detonation: Creating a Playbook for State and Local Planners and Responders

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