Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells-Reference-Cited by-同舟云学术

Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells

Published:2010-02-03 Issue:17 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Saito Yoriko¹,Kitamura Hiroshi²,Hijikata Atsushi²,Tomizawa-Murasawa Mariko¹,Tanaka Satoshi³,Takagi Shinsuke¹,Uchida Naoyuki⁴,Suzuki Nahoko¹,Sone Akiko¹,Najima Yuho¹,Ozawa Hidetoshi¹,Wake Atsushi⁴,Taniguchi Shuichi⁴,Shultz Leonard D.⁵,Ohara Osamu²,Ishikawa Fumihiko¹

Affiliation:

1. Research Unit for Human Disease Models, RIKEN Research Center for Allergy and Immunology, Yokohama, 230-0045 Japan.

2. Laboratory for Immunogenomics, RIKEN Research Center for Allergy and Immunology, Yokohama, 230-0045 Japan.

3. Nippon Becton Dickinson Company, Tokyo, 107-0052 Japan.

4. Department of Hematology, Toranomon Hospital, Tokyo, 105-8470 Japan.

5. The Jackson Laboratory, Bar Harbor, ME 04609, USA.

Abstract

CD32 and CD25, molecules specifically found in human leukemia stem cells, are promising targets for therapy.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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