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A Therapeutic Target for Smoking-Associated Lung Cancer

Published:2010-12-15 Issue:62 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Turner Nicholas C.¹²,Seckl Michael J.³

Affiliation:

1. Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.

2. The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London SW3 6JB, UK.

3. Lung Cancer Biology Group, CR-UK Laboratories, Hammersmith Hospital Campus, Imperial College London, London W12 0NN, UK.

Abstract

A new oncogenic aberration in smoking-associated lung cancer may be the disease's first relatively high-frequency therapeutic target.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference32 articles.

1. Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

2. Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

3. Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer

4. Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

5. Fibroblast growth factor signalling: from development to cancer

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