The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody-Reference-Cited by-同舟云学术

The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody

Published:2012-06-20 Issue:139 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Teoh Ee Ping¹,Kukkaro Petra²³,Teo En Wei¹,Lim Angeline P. C.²,Tan Tze Tong¹,Yip Andy⁴,Schul Wouter⁴,Aung Myint²³,Kostyuchenko Victor A.²³,Leo Yee Sin⁵,Chan Soh Ha¹,Smith Kenneth G. C.⁶,Chan Annie Hoi Yi⁷,Zou Gang⁴,Ooi Eng Eong²,Kemeny D. Michael¹,Tan Grace K.¹,Ng Jowin K. W.¹,Ng Mah Lee¹,Alonso Sylvie¹,Fisher Dale⁸,Shi Pei-Yong⁴,Hanson Brendon J.⁷,Lok Shee-Mei²³,MacAry Paul A.¹

Affiliation:

1. Department of Microbiology and Life Sciences Institute Immunology Programme, National University of Singapore, Singapore 117597, Singapore.

2. Duke–NUS Graduate Medical School, Singapore 169857, Singapore.

3. Center for BioImaging Sciences, National University of Singapore, Singapore 117546, Singapore.

4. Novartis Institute for Tropical Diseases, Singapore 138670, Singapore.

5. Communicable Diseases Center and Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore 308433, Singapore.

6. Cambridge Institute for Medical Research and Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB22XY, UK.

7. Defense Medical and Environmental Research Institute, Defence Science Organisation National Laboratories, Singapore 117510, Singapore.

8. Infectious Disease Division, National University Hospital, Singapore 129793, Singapore.

Abstract

The mechanism of action of a serotype-specific natural human antibody against dengue virus has been identified.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference44 articles.

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