MHC Class I–Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia-Reference-Cited by-同舟云学术

MHC Class I–Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia

Published:2013-09-18 Issue:203 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Cobbold Mark¹²,De La Peña Hugo²,Norris Andrew³,Polefrone Joy M.³,Qian Jie³,English Ann Michelle³,Cummings Kara L.¹,Penny Sarah²,Turner James E.²,Cottine Jennifer³,Abelin Jennifer G.³,Malaker Stacy A.³,Zarling Angela L.¹,Huang Hsing-Wen²,Goodyear Oliver²,Freeman Sylvie D.²,Shabanowitz Jeffrey³,Pratt Guy⁴,Craddock Charles⁵⁶,Williams Michael E.⁷,Hunt Donald F.³⁸,Engelhard Victor H.¹

Affiliation:

1. Carter Immunology Center and Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.

2. Medical Research Council Centre for Immune Regulation and Clinical Immunology Service, School of Immunity and Infection, College of Medicine and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

3. Department of Chemistry, University of Virginia, Charlottesville, VA 22901, USA.

4. Cancer Research UK Institute for Cancer Studies, School of Cancer Sciences, University of Birmingham, Birmingham B15 2TT, UK.

5. Cancer Research UK Clinical Trials Unit, School of Cancer Sciences, University of Birmingham, Birmingham B15 2TT, UK.

6. Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham B15 2TH, UK.

7. Division of Hematology/Oncology and Hematologic Malignancy Program, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

8. Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA.

Abstract

Immunity against phosphopeptide antigens lacking in leukemia patients can be restored with stem cell transplantation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference58 articles.

1. Graft-versus-leukemia effects of transplantation and donor lymphocytes

2. Imatinib plus Peginterferon Alfa-2a in Chronic Myeloid Leukemia

3. Hematologic Remission and Cytogenetic Improvement Induced by Recombinant Human Interferon AlphaAin Chronic Myelogenous Leukemia

4. Graft-versus-leukemia reactions after bone marrow transplantation

5. Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients

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