Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA-Reference-Cited by-同舟云学术

Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

Published:2014-08-20 Issue:250 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Thi Emily P.¹,Mire Chad E.²³,Ursic-Bedoya Raul¹,Geisbert Joan B.²³,H. Lee Amy C.¹,Agans Krystle N.²³,Robbins Marjorie¹,Deer Daniel J.²³,Fenton Karla A.²³,MacLachlan Ian¹,Geisbert Thomas W.²³

Affiliation:

1. Tekmira Pharmaceuticals, Burnaby, British Columbia V5J 5J8, Canada.

2. Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77550, USA.

3. Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77550, USA.

Abstract

Lipid nanoparticle delivery of anti-MARV nucleoprotein–targeting small interfering RNA can treat Marburg virus in nonhuman primates after symptom onset.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference29 articles.

1. H. Feldmann A. Sanchez T. W. Geisbert in Fields Virology D. M. Knipe P. M. Howley Eds. (Lippincott Williams & Wilkins Philadelphia PA 2013) pp. 923–956.

2. Response to Imported Case of Marburg Hemorrhagic Fever, the Netherlands

3. Imported case of Marburg hemorrhagic fever—Colorado, 2008;Centers for Disease Control and Prevention (CDC);MMWR Morb. Mortal. Wkly. Rep.,2009

4. Cryo-Electron Tomography of Marburg Virus Particles and Their Morphogenesis within Infected Cells

5. Establishing Efficacy of Human Products Using Animals

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control;Signal Transduction and Targeted Therapy;2024-09-11

2. An update on nonhuman primate usage for drug and vaccine evaluation against filoviruses;Expert Opinion on Drug Discovery;2024-08-18

3. Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques;Viruses;2024-07-24

4. Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing;Viruses;2023-11-28

5. Marburg Virus- A Threat During SARS-CoV-2 Era: A Review;Infectious Disorders - Drug Targets;2023-08